Saturday, December 28, 2019

French Expressions Using Soir and Soirée

The French words un soir and une soirà ©e both mean evening (we explain the difference here) and are also used in many expressions. Many of the expressions including soir  and soirà ©e  are idioms — phrases with meanings that cant be derived from a direct translation of the words they use. With this list of expressions using soir  and  soirà ©e,  you can learn how to say frequently used sayings like an  evening meal, a night owl, formal wear and more. Common French Expressions With Soir à   prendre matin midi et soirto be taken three times a dayau soir de sa vieto be in the evening of his lifeles cours du soirnight classesà ªtre du soirto be a night owlIl est arrivà © un beau soir.He turned up one evening.le repas du soirevening mealune robe du soirevening gownle soir descend / tombeevening is closing inla veille au soirthe previous eveningVoulez-vous coucher avec moi ce soir  ?Do you want to sleep with me tonight? Common French Expressions Using Soire bonne soirà ©ehave a nice eveningune soirà ©eparty, evening performanceune soirà ©e dansantedance​la tenue de soirà ©eformal wear, evening dressla tenue de soirà ©e de rigueurblack tie

Thursday, December 19, 2019

Essay on Red Lobsters Ethical Dilemma - 2438 Words

Red Lobsters Ethical Dilemma - Term Paper Gerry Mullen, CEO of Red Lobster restaurants, has been faced with a dilemma. He recently received an email from Terry Modotti, Vice President for Public Relations concerning the lobster retrieval in La Mosquitia, also known as the Mosquito Coast. The article states that many of the young working men are being killed and maimed to make lobsters available at cheap process to consumers in the United States. The men, known as buzos, must dive up to 130 feet for lobster, and face dangerous decompression sickness which begins with paralysis and ends in a slow death. This is due to the fact that there are no medical or decompression facilities on the boats, and there is also no equipment to aid†¦show more content†¦Another disadvantage of implementing this option would be that net earnings would decrease due to a decrease in consumers, and shareholders will be angered by the decreasing figures of the company. With all of the negativity being placed upon the company as a resul t of this option, a bad light would be shown on the CEO and the company, especially since Gerry is relatively new. Since there are clearly more disadvantages than advantages for Gerry and Red Lobster by exercising this option, I would advise Gerry to further pursue other options. Another option with which Gerry could investigate would be for Red Lobster to offer to pay a higher price for lobster to boat companies in the Mosquito Coast in order for the divers to receive a higher salary cut. A possible advantage to this is that it would provide a better living environment for the divers. It is stated in the article that after the sacabuzos (middlemen), boat captains, and fish processors take their share of the money, what remains for the buzos is a mere $2 per pound of lobster fetched. Within a two week time period, this rate will amount to about $300. If the divers are trying to support families, $300 for two weeks is quite meager. By increasing the price that Red Lobster is wi lling to pay for wholesale lobster, the divers will benefit considerably due to a higher salary. Another advantage to a higher salary would mean that more individuals would be inclined to become divers,

Wednesday, December 11, 2019

Abnormal Psychology for Alzheimer Disease and Vascula-myassignmenthelp

Question: Discuss about theAbnormal Psychology for Alzheimer Disease and Vascula. Answer: Neurocognitive Disorder Due To Alzheimer's Disease In the neurocognitive disorder due to Alzheimers disease the patients cognitive domains like learning and memory are impaired. There are two types of cognitive disorders like major and minor (Solomon et al., 2014). No cerebrovascular diseases can be found in the medical history. When the disorder is major the patients everyday activities are interfered. The decline in memory is gradually progressive. Generally the age of average people to get affected by this disease is 80 and men survive up to 4.2 years and women 5.7 years (Mentalhealth.com, 2017). Agnosia and Apraxia are common in the disease. Vascular Neurocognitive Disorder This is a neurocognitive disorder due to disruptions in brains blood supply (Elementsbehavioralhealth.com, 2017). The decline of the cognitive happens in fluctuating or stepwise course and there are improved stable period in between unlike the gradual progression neurocoginitive disorder due to Alzheimers disease. Generally grows in a rapid speed after a stroke. History of other cerebrovascular diseases can be found in the medical history. This disorder can be experienced in any age, however the severity increases after the age of 65 and common survival period is 4 years(Mentalhealth.com, 2017). According to Konrth et al, the treatment of Alzheimers disease sees promises in the ICHE Cholinesterase inhibitors drugs as the enzyme proves to be effective. In this drugs quaternary beta-carboline, huperzine, lycorine and aporphyrin alkaloids are used. These chemical groups are generally used in the clinical phase of Alzheimers diseases symptomatic treatment however the researchers are considering changed course and mechanism are being considered. The A oligomers in relationship with enzyme cholinesterase are the source with increased density and subsequesnt neuron disposition. In the conventional practice of treatment Galantamine or Physostigmine alkaloids are used. During the course of Alzheimers, the researchers have been investigating some natural alkaloids in order to identify the changes. Like Triterpene which is a steroidal alkaloid and promotes inhibition of non competitive type, benzylisoquinoline and aporphyrin are isoquinolines that are non competitive and beta carboline s are non competitive (Sun, Jin lin, 2012). On the other hand Huperzine alkaloids such as lycopodium and quinolizidine alkaloids promote inhibition of competitive nature, lycorine, galantamine, physostigmine, monoterpenes and indole alkaloidsa re competitive compounds (Len , Garcia Marco-Contelles, 2013).The authors claim that among so many competitive and non competitive compounds, the huperzine is selective, potent and reversible. This was successfully applied in organophosphate poisoning, myasthenia gravis and schizophrenia. The successful trail of Huperzine resulted in improved in short term memory. However its toxic effects have to be minimized in order to make it more effective. There are other issues related to Huperzine its limited ability to overcome blood brain barrier and it is highly selective. Further detail research and trial will enhance its possibility. According to McGuinnes et al, Allele APOE ?4 expresses the apolipoprotein E subtypes action which is highly potential to effectively link between NPs and A oligomers. GSK 3beta activities can also be increased by it and this can cause tau protein like hyperphosphorylation and NFTs are formed. This protein subtype statines is capable of reducing A plaque formation. This drug is significantly effective in the treatment of Alzheimers disease because of its lipid lowering power. This specialty of Statins makes it a multi target drug. In certain cases of dementia the researchers have found evidences that this subtype reduces systematic cholesterol. The brains cholesterol level can a;lso be controlled by the Statins mechanism which results in reduced NFTs. The physicians have been using Stanits in increased number after it showed positive results in the patients. The Alzheimers patients have been experiencing lower level of dementia after using this drug for a certain period. This drug has also shown signs of crossing the brain blood barrier in more successful manner that other drugs. The usage can also improve the CNS circulation Loci. Howver there are only limited investigations has been observed dutring the course of Alzheimers which successfully makes it the most effective prevetion. Above that if it is applied for a continuous lng period to te Alzheimers patients , it might shows hepatic impairment. The Rhabdomyolysis risk can be increased as well and there are laso safety issues assoviated with the use of Statins. The researchers have conducted a meta analysis and nineteen observational studies to determine the drugs longitudinal and cross sectional actions. The cross sectional observation demonstrates that Statins are really eff ective drugs. The results have also highlighted that Statins is capable of reducing various forms of dementia among Alzheimers disease patients. Feng and Wang (2012) researchers have found that during the course of Alzheimers disease, the oxidative stress causes serious problems for the victims and increases the severity. The NFT or NP progression and increased inflammatory process are enhanced by some glicidic, protein or lipid oxidation. This generally happens prior to pathophysiological treatment. This leads the researchers focus on the antioxidants as a potential preventive element in the Alzheimers disease. They investigated the antioxidant compounds that are capable of treating the preventing the Alzheimers disease. The antioxidant compounds are likely to resist Alzheimers pathophysiological course and hold that capability of reducing the ROS or reactive oxygen species. The a-tacopherol of the vitamin E has gain much attention among the researchers as an effective anti oxidant compound capable of bringing the desired successes. Over a period of 4 years during the treatment course of Alzheimers disease this vitamin E sub stance has shown the evident of lowering the development of Alzheimers. The multiple trials have shown the result between 2.5 and 4.0 fold. However, not many investigations have been done to measure its great potential to become an adjunct of the treatment. Selegiline is another drug that has shown positive sign in the treatment of Alzheimers. the behavior and mood of the Alzhiemers patients have been improved by this drug. This result has been concluded from evaluating by 12 researchers in 8 different trials. Another meta analysis related to the use of the Selegiline has shown that there is also an improvement in the victims memory. The antioxidant qualities and capability of increasing blood circulation of Ginkgo Biloba demonstrated significant result in the treatment of Alzheimers disease. This can also resist synapses reduction and can increase the neurotrophic production related to Alzheimers neuronal apoptosis. This is the reason that the drug is capable of improving the behav ioral qualities by reducing the A induction of the Alzheimers patients. However the researchers have also found that the drug is capable of causing several side effects during the application especially when used during the anticoagulation therapy. There are other antioxidant compounds found in the antioxidants that have demonstrated potentiality in Alzheimers treatment, like Carotenoids of Vitamin C, Omega 3, Vitamin B12, resveratrol, glutathione and palmatine alkaloids. Reference Feng, Y., Wang, X. (2012). Antioxidant therapies for Alzheimer's disease.Oxidative medicine and cellular longevity,2012. Konrath, E. L., Passos, C. D. S., Klein?Jnior, L. C., Henriques, A. T. (2013). Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease.Journal of Pharmacy and Pharmacology,65(12), 1701-1725. McGuinness, B., O'hare, J., Craig, D., Bullock, R., Malouf, R., Passmore, P. (2013). Cochrane review on Statins for the treatment of dementia.International journal of geriatric psychiatry,28(2), 119-126. Neurocognitive Disorder Due To Alzheimer's Disease. (2017).Mentalhealth.com. Retrieved 30 August 2017, from https://www.mentalhealth.com/home/dx/dementiaalzheimer.html Solomon, A., Mangialasche, F., Richard, E., Andrieu, S., Bennett, D. A., Breteler, M., ... Skoog, I. (2014). Advances in the prevention of Alzheimer's disease and dementia.Journal of internal medicine,275(3), 229-250. Sun, X., Jin, L., Ling, P. (2012). Review of drugs for Alzheimer's disease.Drug discoveries therapeutics,6(6), 285-290. Understanding Vascular Neurocognitive Disorder. (2017).Addiction Treatment | Elements | Drug Rehab Treatment Centers. Retrieved 30 August 2017, from https://www.elementsbehavioralhealth.com/health-2/understanding-vascular-neurocognitive-disorder/ Vascular Neurocognitive Disorder. (2017).Mentalhealth.com. Retrieved 30 August 2017, from https://www.mentalhealth.com/home/dx/dementiainfarct.html

Wednesday, December 4, 2019

Lenovos Operations free essay sample

Abstract Leno does all the operations from the cargo to the assembly production, from the product-sells to the post-sale service. This has helped company realize the large scale production and cost efficiency. In sales aspect, the company provides many kinds of purchases and the marketing channels. The customer can directly get the product through the on-line purchase or buy in-directly at large retail stores. These features have helped Leno grow its business and now it is considered the worlds second-largest PC vendor. Physical Distribution Market Exposure For most of us its nearly impossible to go a day without touching a notebook computer. Fast-moving technology has rendered the PC a commodity. Product features are not the differentiator they used to be. A brands emotional connection with the customer and time-to-market advantages are becoming the ultimate gig. An ideal market exposure makes a product available widely enough to satisfy target customers needs but not exceed them and too much exposure only increases the total cost of marketing. We will write a custom essay sample on Lenovos Operations or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page As some product classes require much less market exposure than others. A marketing campaign that provides good marketing exposure is one hat has a high profile. I believe that Leno uses Selective Distribution in selling through only those intermediaries who gives their products special attention. Distribution Customer Service and Direct/lenience Channels Customers dont care how a product was moved or stored or what channel was used to provide it, rather they only think in terms of how rapidly and dependably a firm can deliver what they want. If you want to buy a new Leno computer and the store you went to doesnt have it on hand, youre most likely to buy it elsewhere or switch to some other brand so it is very important for a firm to have the products available or he sale will be lost which adds up to immense loss. Leno distributes through both direct and indirect channels. They have direct-to-customer e-selling option of placing orders by customers on their website and indirect selling of its products through wholesales, retailers and other specialists. Specialization makes the distribution channel more efficient and Leno takes full advantage because trained salesmen can provide in-depth product information to the customers. Additionally specialist channels provide Leno crucial information about customer needs and insights into differences in the current market trends. Wholesalers/Retailers In the USA large Retailers like Walter, Best Buy, Staples, Amazon, Buy. Com, B, Circuit City, Compass, Frys electronics, JR, Disrespect. Com, newest. Com, micrometer. Com Office Depot, and Officemate. At present, Cost is the only wholesaler that Leno sells through. Leno has an extensive network of business partners who are also available to help the customers choose from a range of PCs, accessories and unique technologies. Some of these local resellers in Delaware are Wagon Technology Group, Secure Data Computer Solutions, Inc. , and Hypertext USA. Discrepancies and Separations Sometimes the assortment and quantity of products customers want can be different from the assortment and quantity of products companies produce. Most of the time a customer may need more than Just a laptop or a desktop in order to complete a task, they may also need the accessories to go with the product and usually they dont want to shop for each item separately. In order to pursue this, Leno has enhanced their website and product availability to be a one-stop shop where customers can buy a large range of accessories and upgrades along with Laptops, Tablets, Ultrasound, etc. Laptop bags, speakers, keyboard and mice, software, printers, projectors, servers, storage devices, cameras and scanners are some of the accessories that are widely available on its website for purchase. Leno has a wide range of cheaper to high end models prices for separations of products. Special coordination, parent organization, channel, and supply chain To enable more accurate and timely recording of its sales of Leno products a secure website is provided to facilitate reporting. Leno authorizes its resellers to report weekly sales ND inventory through either the Web tool or via Electronic Data Interchange (DE) and no other forms of reporting is being accepted. Their Purchase orders, shipping reports, and other paper documents are being replaced with computerized DE. Improved information flow and better coordination of physical distribution activities is a key reason for success. Coordinating all of the elements of distribution is a challenge and trying to coordinate orders, inventory, and transportation throughout the whole supply chain is even tougher and EDI offers access to up-to-date information that the company requires. Transportation requirements In an effort to minimize Lenos climate change impact and reduce its carbon footprint, Leno uses local manufacturing facilities in the Americas, Europe and Asia, as well as the lowest carbon shipping methods via truck, rail or sea where possible. Leno is working closely with its shipping partners to ship products responsibly by certified EPA Smarty program for implementing fuel efficient shipping standards. Leno has shifted 7% of its products that are transported by air to ocean transport to minimize environmental impacts related to shipping. Maintaining the right inventory level is often difficult when its hard to foresee the likely demand of a product. Stockpiling allows producers and intermediaries to keep stocks at convenient locations ready to meet customers needs. A convenient location and access to workers with the right skills were critical factors that led Leno to build its first in-house U. S. Distribution and assembly facility in Withiest, N. C. , Just outside Greensboro which also handles reverse logistics. Wave Systems Corp.. And SEED International Holdings are also some of the global distributors that Leno partners with. Reverse Channels Leno has Joined hands with Greenness and RESEARCH, reverse logistics companies, to manage its reverse logistics process. These collaborations provide a dedicated alternate sales channel for their refurbished and take-back products that will not cannibalize Lenos new product sales channels. These channels provide Leno with facilities and processes like brokering, refurbishing, reselling, dismantling, recycling, disposal services, returns and recalls regardless of their geographic location. This is a strategic advancement towards providing cost effective and environmentally responsible return or recalls service. Lenos efficient returns management is rapidly gaining foresight to strengthen their leadership position. New Courses of Action One of the things that I would like Leno to excel is making laptops and ultrasound with increased protection of personal data and safety. These portable devices are prone to theft and certainly theft cases involving these have increased over the past few years to an extent that 1 in 10 laptops will be stolen within its lifetime. It is advised not leave these devices in car at parking lots. Thefts can also occur while traveling at airports, hotels, rental cars, and conference events.